Hexokinase iv regulation mechanism. Download the study materials here- Mammalian hexokinase IV, also referred to as glucokinase, differs from other hexokinases in kinetics and functions. The location of the phosphorylation on a subcellular level occurs when glucokinase translocates between the cytoplasm and nucleus of liver cells. Glucokinase can only phosphorylate glucose if the concentration of this substrate is high enough; its Km for glucose is 100 times higher than that of hexokinases I, II, and III. Hexokinase […]

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