Gene Regulation
031 – Gene Regulation
Paul Andersen explains how genes are regulated in both prokaryotes and eukaryotes. He begins with a description of the lac and trp operon and how they are used by bacteria in both positive and negative response. He also explains the importance of transcription factors in eukaryotic gene expression.
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Bioinformatik, English: Jawahar Swaminathan and MSD staff at the European Bioinformatics InstituteDeutsch: Jawahar Swaminathan und MSD Mitarbeiter am Europäischen Institut für BioinformatikPlattdüütsch: Jawahar Swaminathan un de Lüüd von MSD an dat Europääsche Institut för. English: Cartoon Representation of the Molecular Structure of Protein Registered with 2nvw Code., [object HTMLTableCellElement]. English: displayed on
DNA, n.d.
“File:E Coli at 10000x, Original.jpg.” Wikipedia, the Free Encyclopedia, November 13, 2013.
“File:Glass of Milk on Tablecloth.jpg.” Wikipedia, the Free Encyclopedia. Accessed December 1, 2013.
“File:Lac operon1.png.” Wikipedia, the Free Encyclopedia. Accessed December 1, 2013.
“File:Protein TBP PDB 1c9b.png.” Wikipedia, the Free Encyclopedia. Accessed December 1, 2013.
“File:Ribosome mRNA Translation En.svg.” Wikipedia, the Free Encyclopedia. Accessed December 1, 2013.
Forluvoft. Simple Cartoon of Transcription Termination, October 9, 2007. Own work.
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so good
Thank you so much this is really sooooooooooooooo helpful!!!
I think you may have made a mistake about the positive and negative controls of gene expression
so helpfull, i hope u have a great day!!! (9^_^)9
Among Us?
Dude I live in India and in my high school i almost spent a day or 2 just trying to figure out this operon..reading tens of books but still couldn't understand much. I now realise this is what it means to be a teacher how u explained it marvellously! Me being an average student no teacher near me really cleared my doubts but thank you for ur efforts!!❤
YOU'VE SAVED MY GRADES, THANK YOU, YOU'RE AMAZING!!!
i love you
Nice 👍
8:20 Hi Mr. Anderson, Would you do a video on junk DNA? Thank you and best wishes.
Very informative. Thanks for sharing, Lord-Jesus-Christ com
Thank you mr. You are helping me with my IB Biology studies. Thank you very much! God bless you!
my fav utuber
so helpful, thank you Mr. Anderson
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Jesus died for you!
Excellent explanation
Mans is the only reason why i have an A in AP biology
Cram ten min before quiz
Great vid, nicely explained!
this is fucking insane
Bless you sir lol
God's handywork!
You saved me
Since middle school and now med school you’ve bean there for me thank you 😂😌
i love you
been watching your videos for two years…always a GREAT help. Thank you so much, Professor!
Instructions not clear. I ate bacon and ecoli and got huge pp
thank you
Lac Operon is an example Inducible proteins not repressible
The mRNA that is made is a single RNA though- each with its own ribosome binding spot- it is called a polycistronic message. Just to be accurate
cramming the night before the ap exam 🙂
Thanks the man of all trades for your wonderful explanation.
i just couldn't listen and had to repeat the video cause i was staring at Paul the whole time… dat jawline….
Thanks
Both lac operon and trp operon are negative control operons because repressors are involved. However, the lac operon is inducible (induced by allolactose) whilst the trp operon is repressible (corepressor tryptophan).
Thanks
your videos are great but it's really horrible when you use the word engineering to describe evolution– which is the opposite of engineering. We know that organisms which do not survive get selected out. The remaining organisms constitute the entirety of the collective genome. Thus biological solutions are not actively created but are what's left when everything else that doesn't work is removed. This is expressed in evolutionary biology by the increasing size of the organisms genomes in time (ie the increasing complexity of life). The increasing informational entropy of the collective genome allows for adaption to occur, without having to actively design a functional solution. In fact, functional solutions are the anti-thesis of evolution, by decreasing the informational entropy of design in order to achieve a specific task. When you say organisms have been engineered, you seem ignorant to the fact that a multitude of variants of this system once existed, or had the potential to exist, but either went extinct, or fail to be expressed. In life, there is no explicit trait which defines survival, but rather the ability for the traits to be modified (which is even expressed in this video), ie adaptation.